Some Studies On Immune Response Of Cattle And Buffaloes vaccinated By Foot And -mouth Disease vaccines Inactivated By Different Chemical Inactivators

F.ur ba’tchea of FMD vaccinee were prepored using four different 1nactivators 11Q]lely: AEI, EEI~ El and formalin. ~e vaecines pr~ved to be sterile. iW1ocuous andimmunogenie.Fixed doses of FMDV particles ranging ”between 100-120~llions were incorporated in each vaccine dose of 5 ml,rngnrdless of the batch of vaccine prepared.anty fully subeeptible cows were divided into fourgroups, ot 5 anima1s each, the onimls of each group71erG vaccinated with one of the prepared FMD vacc Lne a ,Each anf.ma), received a 5 m L, dose inj ected subcutaneouslyin the dewlap_ The immune response of these 4nimals to raco Ino td on by J p r i.mar-y dose of the FMD vo cc Lnes was investigo ted using tlle serum nt$utrolizati::m test (SNT)nd indirect complement fixa·~lon test (IC1!’T).~Jth~r twent3 flly usceptible buffaloes were alSO divided and Lnocu La t e d with t he same FMD vacc Lne ein