| Abstract: |
Seven susceptible 1amnbs inoculated intrHvenously and intrana.sally with DVD-UJ (Eg.~’ptian Hena strain). ’rhe infection spread to contact con’ rol lambs and the contact contro] calf. The clinical manifestation in lambs were mainly r e s p i r-a t o i-yin na ture incl uding nasal d i:jcharge, cough and pyre x.i a •The contact calf sho~cd na~al discharge, salivution, luchry-mation, congestion and erosion on the gum mucou~ membrane.HaematologicD.l, enzYluatological and biochemicnl »t uo i e s were concluded, rn i Ld JcucopeniD. noticed in Lhel;:mbs and the calf followed by an ~ncrease in total leuco- cytic c o un t , ab~;olutc Lytn pho cy t j r, count, :lUIJ, {:;lobu]in , Aspartate amino-transfr-r&fJe ALT and Al)’ni11e ’,mLl”trllnsferase, and cleCreUEje in ’;;’ythrocytic count, .lIb, PCV and a Lbr.mf n .Gro ”;ly the Lung l;is~;ue wa r: oedematous with patchy haemorrhilgic areas. =n liver, f’o c a L, small pin h es.d e d v/hitish foci v/ere noticed. S p I een and lymph node s a p ne > rnnlarger in f3ize than the normal. ’.’111.Ue kidney appeared sfnl-ill&r in si21.:ic1’o s c o pi c a Ll.y , lymphocytic r::e U ac;greca tion wi t ht’ibrobla~;tic proliferation vrer e observed ill the portal ureawi t h necrobiotic chance.s in the hepatocytes and hyperplasticac t i vu t i on of the !’.upffcr eel):;. Pnribronchial, peribronchitis
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