studies on the relation between the humoral antibody response and protection in animals immunized with foot and mouth oil adjuvant vaccine

The immunogenic capacity of the current. FMD aluminium gel vaccine was studied under experimental and fieldconditions in 371 cattle and buffaloes 2- It was revealed that gel vaccines provoke relatively low antibody titres which were likely to withstandinfection for about 4 months post-vaccination.3- A suitable antigen was prepared from strain °1/2/72Egypt and tested for infectivity, antigenicity and140 S particle content. Trials then were made to formulate an oil emulsion vaccine using some available local chemicals in comparison with standard Difco incomplete Freund’s adjuvant. 4- The prepared oil vresults corresponded to 75-100 percent protection in cattle and buffaloes.5- Immune assay of antibodies developed in 4 vaccinated cattle and 4 buffaloes - using oil vaccinee -presented much improved titres which were likelyto be maintained for several months.