Study of repeated administration of some compounds & resulting toxicity on changes of chicken kidney & liver & on the level of serum enzymes

In Egypt poultry now is considered as an importantsource of animal protein9 the use of food additives orconditioning drugs to its ~ation in order to increasetheir production attracted our attention to study thetoxic action that may occur• as a result ’of addition ofsome of these c-ompounds (Catos8.l and arrhynal) thatare added for the previous reason on chicken. Our studyincludes 3 parts:The’ first part deals w i, th t he toxicity and symp-tomes of both compounds in cocks. from our study itcan be concluded that the LD50 of butaphosphan incocks is 9. 974 g/kg B. wt. Signs of butaphosphan toxicj_tyincludes depression, incoordination and diarrhoea, thenthe cocks laid down unable to move with DROPed wings,respiration was rapid followed by gasping and death.While the calculated LD50 for the disodium methyl arse-nate was found to be 2.245 g/kg B.wt. Symptomes of tox-icity were lamness and staggering gait, whitish diarrh-oea and thirst then the cocks laid down motionless witttheir peak on the ground. Respiration was sha.Ll.ow, .~apidirregular followed by death.