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Adenine and benzimidazole-based mimics of REP-3123 as antibacterial agents against Clostridium difficile and Bacillus anthracis: Design, synthesis and biological evaluation
Faculty
Pharmacy
Year:
2016
Type of Publication:
ZU Hosted
Pages:
Authors:
Kamel Abdelrehem Metwaly Bayomy
Staff Zu Site
Abstract In Staff Site
Journal:
Bulletin of Faculty of Pharmacy Cairo University Elsevier
Volume:
Keywords :
Adenine , benzimidazole-based mimics , REP-3123 , antibacterial agents
Abstract:
As part of our ongoing research efforts to develop new antibacterial agents acting on novel molecular targets, a series of twenty-two adenine and benzimidazole-based mimics of the lead compound REP-3123 was designed to target methionyl-tRNA
Author Related Publications
Kamel Abdelrehem Metwaly Bayomy, "Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study", ELSEVIER, 2017
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Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone‑based rhodanines", Springer Open, 2017
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Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016
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Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", Journal of Enzyme Inhibition and Medicinal Chemistry, 2016
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Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone-based rhodanines", Springer, 2017
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Department Related Publications
Sobhi Mohamed Mahmoud Ibrahym, "Determination of some Pharmaceutical Carbonyl Compounds", لايوجد, 1900
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Mohammed Alhuseiny Abdelhamid Elsadek , "Continuation For Chemical Methods For Analysis of Some Antibiotics", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "Stability indicating spectrophotometric method for determination of Moexipril HCl ", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "Synthesis of new 1,2,4-Triazoloquinazoline derivatives as CNS modulators ", لايوجد, 1900
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Abdallah Ahmed Abdallah Elshanawany, "HPLC Determination of Amoxicillin,Metronidazole and pot. clavulanate in combination mixture in presence of their degradation products ", لايوجد, 1900
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