The antimitotic pyrimido[4,5-c]quinolin-1(2H)-one scaffold: probing substituents at position 3

Faculty Pharmacy Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Kamel Abdelrehem Metwaly Bayomy
Journal: Medicinal Chemistry Research Springer Volume:
Keywords : , antimitotic pyrimido[4,5-c]quinolin-1(2H)-one scaffold: probing substituents , position    
Abstract:
As a continuation of our efforts to optimize the antimitotic effect of our pyrimido[4,5-c]quinolin-1(2H)-one scaffold, we were interested in exploring the SAR of substituents at position 3 of this fused ring system. Target compounds 2a–r ha
    
     
 
       

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