. Synthesis, in-vitro Cytotoxicity, and a Preliminary Structure-Activity Relationship Investigation of Pyrimido[4,5-c]quinolin-1(2H)-ones

Faculty Pharmacy Year: 2010
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Archiv der Pharmazie Wiley-Interscience Volume:
Keywords : , Synthesis, in-vitro Cytotoxicity, , , Preliminary Structure-Activity Relationship    
Abstract:
As part of our ongoing research effort to develop new antimitotic agents based on the recently reported pyrimido[4,5-c]quinoline-1(2H)-one ring skeleton, we were interested in identifying structural elements that contribute to the cytotoxic
   
     
 
       

Author Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study", ELSEVIER, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone‑based rhodanines", Springer Open, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone-based rhodanines", Springer, 2017 More

Department Related Publications

  • Abdallah Ahmed Abdallah Elshanawany, "Development and validation of liquid chromatographic method for simultaneous determination of amiloride hydrochloride and hydrochlorothiazide in human urine", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "HPLC Determination of polymyxin sulphate, Benzalkonium chloride, and gramicidine in pharm.formulation ", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Synchronous Spectroflurimetric Determination of Famtidine,Fluconazole and Ketoconazole in bulk powder and in pharmaceutical dosages forms ", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Synthesis of 3- substituted (6-bromo-2-imidazo{4,5-b}pyridinyl)propionic acid as antiinflammatory agents. ", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Application of difference spectrophotometry to the nitrosation reaction in the assay of certain antipyretic drugs . ", لايوجد, 1900 More
Tweet