Ketanserin and spiperone as templates for novel serotonin 5-HT2A antagonists

Faculty Pharmacy Year: 2002
Type of Publication: ZU Hosted Pages:
Authors:
Kamel Abdelrehem Metwaly Bayomy
Journal: Current Topics in Medicinal Chemistry BenthamSciences Volume:
Keywords : Ketanserin , spiperone , templates , novel serotonin 5-HT2A    
Abstract:
The structures of ketanserin (1) and spiperone (2) were examined in detail to determine the role of various substituent groups on 5-HT(2A) receptor affinity and selectivity. It was found that the presence of the quinazoline ring of ketanser
    
     
 
       

Author Related Publications

  • Kamel Abdelrehem Metwaly Bayomy, "Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study", ELSEVIER, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone‑based rhodanines", Springer Open, 2017 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", taylor and francis online, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives", Journal of Enzyme Inhibition and Medicinal Chemistry, 2016 More
  • Kamel Abdelrehem Metwaly Bayomy, "Synthesis and anticancer activity of novel quinazolinone-based rhodanines", Springer, 2017 More

Department Related Publications

  • Mansour Alsayed Mansour Abokol, "Synthesis of certain Arylalkanoic Acid Derivatives of pharmacutical Interest", لايوجد, 1900 More
  • Mahmoud Mohamed Mohamed Sebaee, "Poly (vinyl chloride) matrix membrane sensors for the quantification of olopatadine and oxeladine in pharmaceutical preparations and human plasma", Elsevier, 2019 More
  • Noha Ibrahiem Elsayed Mohamed Zidain, "The Utility of isatoic anhydrides in the synthesis of New Heterocycl Compoud For Biological Study", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Development and validation of liquid chromatographic method for simultaneous determination of amiloride hydrochloride and hydrochlorothiazide in human urine", لايوجد, 1900 More
  • Abdallah Ahmed Abdallah Elshanawany, "Development and validation of RP-HPLC for Simultaneous determination of amiloride,hydrichloride,Atenolol,hydrochlorothiazide and chlorthalidone in their combined mixtures ", لايوجد, 1900 More
Tweet