Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding

Faculty Pharmacy Year: 1998
Type of Publication: ZU Hosted Pages:
Authors:
Kamel Abdelrehem Metwaly Bayomy
Journal: Journal of Medicinal Chemistry ACS Volume:
Keywords : Spiperone: influence , spiro ring substituents , 5-HT2A    
Abstract:
Spiperone (1) is a widely used pharmacological tool that acts as a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Although spiperone also binds at 5-HT2C receptors, it is one of the very few agents that display some
   
     
 
       

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