6-Methylpurine Derived Sugar Modified Nucleosides: Synthesis and Evaluation of their Substrate Activity with Purine Nucleoside Phosphorylases

Faculty	Science	Year:	2016
Type of Publication:	ZU Hosted	Pages:
Authors:	Abdullah Elsayed Abdullah Hassan Staff Zu Site Abstract In Staff Site
Journal:	Bioorganic Chemistry Elsevier	Volume:

Keywords :	6-Methylpurine Derived Sugar Modified Nucleosides: Synthesis
Abstract:	6-Methylpurine (MeP) is cytotoxic adenine analog that does not exhibit selectivity when administered systemically, and could be very useful in a gene therapy approach to cancer treatment involving Escherichia coli PNP. The prototype MeP r

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