Evaluation of the immune response of clostridial vaccines in sheep

Immune response in guinea-pigs:10 The total serum protein and total Ig were increased after vaccination crf guinea-pigs but this increase was higher in guinea-pigs vaccinated with whole-culture formalized vaccinethan those vaccinated vdth bacteria-free supernate. 2. The electrophoretic values in pooled sera of all vacci-guinea-pigs revealed a moderate elevation in alpha, beta gamma globulins but the elevation was relatively higher in groups vaccinated with whole culture formalized vaccines.3. The electrophoretic analysis of pooled sera in tetanus vaccinated group showed a sharp DROP in albumin fromto 40.11% :and great increase in alpha, beta and gamma than the! other vaccines