Pathological studies on horses experimentally infected with african horsesickness virus

1 - Five s:steptible horses were inj0cted interven- ously ’,d t.h 5 c. v. AHS-infe c t o d blood type 1.2 - The fil’st sign of illness was elev2tGd body temperature accul’ed between the fourth and thesexth day post-inocnlation.J - Tllc nercmj.c stage 12stGd betr.’een three to five ’(lays dur i ng which the animals app o t I te wa swithin the ~oI’mal limit.4 - The virus titeI’ of ~he vlrGmic blood of hlOt1 lOG.? lOG. 9 107•5rC:Jpectirely.5 - Tlle cli.uicQl s~’m;’ltoms we r e bulginc of the Supra-orbital 1’08[3ae, COl1Destion and inflllITlIAation ofthe coni.:enctira qnd the eye lids, incrense of theInc1’i1:][11 disc)wrge wh i.c h may be :Jeyous or hemo-’tn.”)lrlGlC, e:~tGndillG and DROP)in;,.; of I;11G’ bend and neck,dilnted nostrils w.i t11 mW3nJ. discharGe, e de ma V/lJ.Sa.l eo In’C’sent in t ho f’o ro +ho a d ’t h o paro t i d J ’ogionand the in :,crm:-mdi bulur 81’; .c o • The subcll taneou 8eden::. mny excGnd to t1-1G ventr2l GSpGct of tllG neckarid the br i sko t , The o.niH:uln may stand with1:11e.i1’ lE?gs sprGQdinc apar-r ,T1w lYlovef!1Gnt of the nnimals I’/[lS sbiCCish and.:iff’icult wit l: SGvere clepressi.on and signs of pain