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Studies on the use of ”komarov ” strain for the possible production of duck adapted vaccine against newcastle disease virus
Faculty
Veterinary Medicine
Year:
1975
Type of Publication:
Theses
Pages:
115
Authors:
Nadia M Hassan
BibID
10092483
Keywords :
Veterinary Microbiology
Abstract:
The present’study is concerned ~ath the use of embryonated duck eggs for subsequen t production of ”Komar-ov ”ND vaccine. The aim of this study is to find out asolution for the problem assooiated with the pathogeniooontaminants which oould be transmitted trans-ovariallywhen using embryonated chicken eggs. CL’he first experi-mental part had dealt with the study of the most suitableconditions of the propagated Komarov strain in emb~ona- ted duck eggs~ The second experimental part was assooiatedwith the studies on some pathogenic charaoteristic of theyielded Virus, while the third experimental part was planned to evaluate the immunogenicity of the vaccine. These experiments gave the following results:Part One: 1) The most suitable virus concentration to injectduck embryo was 10-3 ELD50 giving an infeotive titre of10-8·6. 2) The suitable age of developing duck embryo forvirus production was 11 days.3) The optimal inoubating temperature Was 37°0.
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