Some Toxicological studies on withania somnifera plant

The poisonous plant VfITHANIA SOIJINIFERA used in our workwas collected during February & September from Giza Province,Egypt •The total and relative moisture. fat. ash, acid, insolub-le ash and total nitrogen of different parts of this plantwere detelJmined •A prelimanary examination of the reaction and the activeconstituents of air dried powdered seeds, leaves. stems of th-is plant was carried out •The dose response curve of alkaloidal extract of WITH~~IASONiNIFERA inj ected subculanously have been assessed in whiterats •The sYmptoms of toxicity in these animals have been st-udied and deseri bed •The antibacterial effect of alkaloidal extract of WITI:::;’NlkSOI.IHIFERA Cl bo th gram negative and gram posi ti ve organism.a t