Some Toxicological studies on gossypol

Many of the farm animals are subjected to gossypolpoisoning. Its main source is cottonseed and its by-prJLucts. The aim of this study was to investigate the”..ioxicological effect of gossypol and pathological changesrasulting in the body of the poisoned animals.Two main fact should be take n in consideration:The first; is that gossypol was not available, duringthe performance of this study, as a pure material.Therefore several experiments wele applied that enabledselection of most suitable method for isolating gossypolin the most simple way regarding the available chemicals•Extr acti on was car riea out from cott on seed; und ecor tic-’ated and de cor ticated. c ottonseed caks , and cott on seedgums , These selected methods, were subjected t.J certainmodifications to avoid tedious and complicated steps,beElide saving time anc chemicals used. 1’b3 se modific ....<=””;i008 are described in details.Secondly, choice of rabbit as an experimentalanimal was due to thd fact that it is, as stated inliterature, one of the most susceptible animals forgoss3Pol poisoning.