the role played by oxtocin in regulation of luteinizing hormone

The aim of the present study was to find the effects of cdministration of oxytocin on the relense of endogenous1H cud clecrance of exoge.nous LIt preparation from the cir-culation. As oxytocin hos e very short biological hclf-life the design forshort dur [’ t ion.collection of samples was ofFor this purpose 240 mct ur e male rats of on e ve r ag ebody weight of 200 gwer~ used. Hnlf the number of theserats were orchidectomized, ~hile the resttheir testes intact.rem~ined withThe r.n Lmo Ls were divided into three main sets. Thefirst set w as composed of 48 int act r2ts an d r-n ot he r 48ccstrated rats. Thirty six animcls in both cases wereinjected intravenously through the dorsal caudal vein with1.0 i.u. oxytocin. ”Respective cotrols of 12 animels eachwere injected with saline. The pituiteries and serB ofcontrol Dnd oxytocin-treated nnimals were obttA.B.d indivi-dually after 5,20 and 40 minutes.The s e c ond set of exp er Leien t s Lnc Lude d 36 na tur e mal eintoct r2to and cnother 36 dcstrnted rats. These anioolswere injected intravenously with 100. i.u. HOG. The serQand pituitqries were collectad individually et 5.20 and40 minutes after injection of nOG.