Efficient synthesis of N-acylbenzotriazoles using tosyl chloride: en route to suberoylanilide hydroxamic acid (SAHA)

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Journal: General Papers General Papers Volume:
Keywords : Efficient synthesis , N-acylbenzotriazoles using tosyl chloride: en    
Abstract:
Various carboxylic acids were converted into N-acylbenzotriazoles (90-97 % isolated yields) via a one-pot synthesis involving activation of carboxylic acids with tosyl chloride. The novel protocol enabled stepwise manipulation of both car
   
     
 
       

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  • Tarek Mohamed Salah Rashad, "Synthesis of certain 1,2,3,-Benzotriazine Derivatives of Pharmaceutical Interest", لايوجد, 1900 More
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