GSK-3 heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Am J Physiol Heart Circ Physiol Am J Physiol Heart Circ Physiol Volume:
Keywords : GSK-3 heterozygous knockout , cardioprotective , , knockin mouse    
Abstract:
Glycogen synthase kinase- 3 (GSK-3) plays a central role in both cardiac physiology and pathology. Herein we want to clarify the role of GSK-3 in familial dilated cardiomyopathy. We generated a mouse model carrying a heterozygous kno
   
     
 
       

Author Related Publications

  • Eslam Ahmed Abdelhamid ebrahiem, "β-arrestin-mediated signaling improves the efficacy of therapeutics.", J-STAGE, 2012 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Sildenafil protects against bile duct ligation induced hepatic fibrosis in rats: Potential role for silent information regulator 1 (SIRT1)", ُElsevier, 2017 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Hesperidin protects against stress induced gastric ulcer through regulation of peroxisome proliferator activator receptor gamma in diabetic rats", ELSEVIER, 2018 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Ameliorative effects of clonidine on ethanol induced kidney injury in rats: Potential role for imidazoline-1 receptor.", zagizag, 2018 More
  • Eslam Ahmed Abdelhamid ebrahiem, "Carvedilol protects against hepatic ischemia/reperfusion injury in high-fructose/high-fat diet-fed mice: Role of G protein-coupled receptor kinase 2 and 5", Science direct, 2019 More

Department Related Publications

  • Dalia Mohamed Abdelmoteleb Ali, "Renoprotective effect of Hypericum perforatum against diabetic nephropathy in rats: Insights in the underlying mechanisms", Weily, 2017 More
  • Dalia Mohamed Abdelmoteleb Ali, "Comparing the effects of MSCs and CD34+ cell therapy in a rat model of myocardial infarction", Wiely, 2016 More
  • Sahar Kamal Younis Aly, "Harnessing Dual Power: Genistein-Loaded Pumpkisomes in Pullulan Microneedles for Potent Antioxidant and Anticancer Therapy Against Ehrlich Ascites Carcinoma and Breast Cancer Cells", MDPI, 2025 More
  • Shereen Samy Mahmoud Osman, "PROTECTIVE EFFECTS OF IVABRADINE (ALONE AND COMBINED WITH ATENOLOL OR ENALAPRIL) ON EXPERIMENTALLY-INDUCED ACUTE MYOCARDIAL INFARCTION IN ALBINO RATS", Zagazig University, 2017 More
  • Sahar Kamal Younis Aly, "Revealing how phenytoin triggers liver damage and the potential protective effects of Balanites Aegyptiaca fruit extracts: Exploring Nrf2/MAPK/ Beclin-1 signaling pathways", ELSEVIER, 2023 More
Tweet