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GSK-3 heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy
Faculty
Pharmacy
Year:
2016
Type of Publication:
ZU Hosted
Pages:
Authors:
Eslam Ahmed Abdelhamid ebrahiem
Staff Zu Site
Abstract In Staff Site
Journal:
Am J Physiol Heart Circ Physiol Am J Physiol Heart Circ Physiol
Volume:
Keywords :
GSK-3 heterozygous knockout , cardioprotective , , knockin mouse
Abstract:
Glycogen synthase kinase- 3 (GSK-3) plays a central role in both cardiac physiology and pathology. Herein we want to clarify the role of GSK-3 in familial dilated cardiomyopathy. We generated a mouse model carrying a heterozygous kno
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