GSK-3 heterozygous knockout is cardioprotective in a knockin mouse model of familial dilated cardiomyopathy

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Am J Physiol Heart Circ Physiol Am J Physiol Heart Circ Physiol Volume:
Keywords : GSK-3 heterozygous knockout , cardioprotective , , knockin mouse    
Abstract:
Glycogen synthase kinase- 3 (GSK-3) plays a central role in both cardiac physiology and pathology. Herein we want to clarify the role of GSK-3 in familial dilated cardiomyopathy. We generated a mouse model carrying a heterozygous kno
   
     
 
       

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