Studies on quinuronium sulphats preperations (acaprin and pirevan ) with special references on haematological and toxicological changes in rat

The Purpose of this study is to investigate some of the toxicological,haeOlatological, biochemi.cal andhtst.opathological aff90ts of Acaprin and Pirevan as the most famous babesicidal prep6~ati0ns of the Quinuronium sulphate oompound •Av1alable lit6ratu~e about QuiDuroniu~ qulphatshistory, chemistry, pha rmaco Logy , therapeutic uses,side effects and toxicological effects on hapatic function and bleod parameters is revia~ed.Animals used in this experimetrli WArs Albino rat. The techtliql1,.6s app Ll e d , preparation of reagents for determi~1a-tion of enzyme {lctivi ty and for haematological studiesare described in details in the part dealing with material and methods.SOIne re su Ltrs of these iDv8stig~tiol”ls, seemed J.nJGtJrst-log, and are therefore summarized as follows :Toxicological results:Toxic action of both Acaprin and Piravan was investigated, their toxic 9ffscts was demonesterated