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INTRANASAL MICROEMULGEL AS SURROGATE CARRIER TO ENHANCE LOW ORAL BIOAVAILABILITY OF SULPIRIDE
Faculty
Pharmacy
Year:
2016
Type of Publication:
ZU Hosted
Pages:
188-197
Authors:
Mahmoud Abdalghany Mahmoud Mahdy
Staff Zu Site
Abstract In Staff Site
Journal:
International Journal of Pharmacy and Pharmaceutical Sciences Innovare Academic Sciences Pvt Ltd
Volume:
10
Keywords :
INTRANASAL MICROEMULGEL , SURROGATE CARRIER , ENHANCE , ORAL BIOAVAILABILITY
Abstract:
Objective: The purpose of this study is to evaluate microemulsion based gel (MBG) of sulpiride "a poorly water soluble antipsychotic with low oral bioavailability." Methods: Gelling polymers such as sodium carboxymethylcellulose (CMC-Na),
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