PARP-1 inhibition alleviates diabetic cardiac complications in experimental animals

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages: 444-454
Authors:
Hany Mohamed Abdelmalek Mahmoud ElBassossy
Journal: European journal of pharmacology Elsevier Volume:
Keywords : PARP-1 inhibition alleviates diabetic cardiac complications    
Abstract:
Cardiovascularcomplicationsarethemajorcausesofmortalityamongdiabeticpopulation.Poly(ADP- ribose) polymerase-1enzyme(PARP-1)isactivatedbyoxidativestressleadingtocellulardamage.We investigatedtheimplicationofPARP-1indiabeticcardiaccomplicat
    
     
 
       

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