Effect of prolactin on synthests, release & turnover of gonadotrophins

The literature on prolactin (LTH) fs rather con- flicted and confused. The aim of the presant investig-ation is to clarify some aspects of the effects of prolactin on gonadotrophins and the male reproductive activity.Prolactin was prepared from bovine pituitaries.The preparation oontained. 4.75 i.u. prolactin per mg (crop sac method).Two main groups of adult male rats were used.The first was divided into nine groups and. designed to investigate the effect of prolactin, testosteronepropionate (TP), testosterone propionate plus prola~ tin, Luteinizing hormone (LH), luteinizing hormoneplus prolactin and antiprolactin serum on male repr- oductive organs and on gonadotrophins. The secondmain group was planned to stud.y the effect of pro la-ctin and. antiprolactin serum on synthesis, release and. turnover of gonad.otrophins.