Combination of sitagliptin and insulin against type 2 diabetes with neuropathy in rats: neuroprotection and role of oxidative and inflammation stress

Faculty Medicine Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Journal: Pharmacology Pharmacology Volume: 95
Keywords : Combination , sitagliptin , insulin against type , diabetes    
Abstract:
Abstract Aims: The present study evaluated the effects of sitagliptin-insulin against T2DM with neuropathy in rats and possible neuroprotective mechanisms. Methods: Diabetes was induced in 32 adult male albino rats by 6-week high-fat high-
   
     
 
       

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  • Mohamed El Sayed Kelany, "Comparative Glucose-Lowering and Renoprotective Effects of Sitagliptin and Insulin and their Combined Therapy on Type-2 Diabetes Mellitus with Nephropathy in Rats", Zagazig University Medical Journal, 2015 More
  • Mohamed El Sayed Kelany, "Protective effects of combined β-caryophyllene and silymarin against ketoprofen-induced hepatotoxicity in rats", Can. J. Physiol. Pharmacol., 2016 More
  • Mohamed El Sayed Kelany, "Evaluation of the antiulcer effect of nitric oxide against experimentally-induced gastric ulcer in rats.", Zagazig University Medical Journal, 2008 More
  • Mohamed El Sayed Kelany, "Antioxidant and antiapoptotic effects of combined Sidr honey and Nigella sativa oil against paracetamol-induced hepato-nephrotoxicity in rats", Zagazig University Medical Journal, 2016 More
  • Mohamed El Sayed Kelany, "Role of the antidiabetic drugs: Glibenclamide and metformin on the contractility of isolated rat uteri", Pak. J. Pharm. Sci, 2016 More

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