Selective and Orally Bioavailable CHK1 Inhibitors of Some Synthesized Substituted Thieno[2,3-b]pyridine Candidates

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Hassan AbdelFattah Mohammed
Journal: International Journal of Pharmacology www.ansinet.com Volume:
Keywords : Selective , Orally Bioavailable CHK1 Inhibitors , Some    
Abstract:
A series of the newly substituted thienopyrimidine derivatives 2-13 were synthesized by using 3-amino-6-(4-chlorophenyl)-4-(4-isopropylphenyl) thieno[2,3-b]pyridine-2-carbohydrazide 1 as starting material. Reaction of compound 1 with p-nitr
    
     
 
       

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