Selective and Orally Bioavailable CHK1 Inhibitors of Some Synthesized Substituted Thieno[2,3-b]pyridine Candidates

Faculty	Science	Year:	2015
Type of Publication:	ZU Hosted	Pages:
Authors:	Hassan AbdelFattah Mohammed Staff Zu Site Abstract In Staff Site
Journal:	International Journal of Pharmacology www.ansinet.com	Volume:

Keywords :	Selective , Orally Bioavailable CHK1 Inhibitors , Some
Abstract:	A series of the newly substituted thienopyrimidine derivatives 2-13 were synthesized by using 3-amino-6-(4-chlorophenyl)-4-(4-isopropylphenyl) thieno[2,3-b]pyridine-2-carbohydrazide 1 as starting material. Reaction of compound 1 with p-nitr

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