Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice.

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Eman Salah Abdelaziz Souliman
Journal: Prostaglandins Leukot Essent Fatty Acids Elsevier Volume:
Keywords : Apigenin inhibits COX-2, PGE2, , , , also initiates    
Abstract:
Non-melanoma skin cancer (NMSC) is the most prevalent cancer in the United States. NMSC overexpresses cyclooxygenase-2 (COX-2). COX-2 synthesizes prostaglandins such as PGE2 which promote proliferation and tumorigenesis by engaging G-protei
    
     
 
       

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  • Eman Salah Abdelaziz Souliman, "Arachidonoyl-ethanolamide activates endoplasmic reticulum stress-apoptosis in tumorigenic keratinocytes: Role of cyclooxygenase-2 and novel J-series prostamides.", wiley online library, 2016 More
  • Eman Salah Abdelaziz Souliman, "Receptor-dependent and receptor-independent endocannabinoid signaling: a therapeutic target for regulation of cancer growth.", Elsevier, 2013 More
  • Eman Salah Abdelaziz Souliman, "Anandamide-induced endoplasmic reticulum stress and apoptosis are mediated by oxidative stress in non-melanoma skin cancer: Receptor-independent endocannabinoid signaling.", wiley online library, 2016 More

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