Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice.

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Eman Salah Abdelaziz Souliman
Journal: Prostaglandins Leukot Essent Fatty Acids Elsevier Volume:
Keywords : Apigenin inhibits COX-2, PGE2, , , , also initiates    
Abstract:
Non-melanoma skin cancer (NMSC) is the most prevalent cancer in the United States. NMSC overexpresses cyclooxygenase-2 (COX-2). COX-2 synthesizes prostaglandins such as PGE2 which promote proliferation and tumorigenesis by engaging G-protei
    
     
 
       

Author Related Publications

  • Eman Salah Abdelaziz Souliman, "Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ12,14-Prostamide J2, as a Selective Antitumor Therapeutic", American Associatiion of Cancer Research, 2017 More
  • Eman Salah Abdelaziz Souliman, "Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms", Experimental Pharmacology and drug discovery, 2017 More
  • Eman Salah Abdelaziz Souliman, "Arachidonoyl-ethanolamide activates endoplasmic reticulum stress-apoptosis in tumorigenic keratinocytes: Role of cyclooxygenase-2 and novel J-series prostamides.", wiley online library, 2016 More
  • Eman Salah Abdelaziz Souliman, "Receptor-dependent and receptor-independent endocannabinoid signaling: a therapeutic target for regulation of cancer growth.", Elsevier, 2013 More
  • Eman Salah Abdelaziz Souliman, "Anandamide-induced endoplasmic reticulum stress and apoptosis are mediated by oxidative stress in non-melanoma skin cancer: Receptor-independent endocannabinoid signaling.", wiley online library, 2016 More

Department Related Publications

  • Rasha Hassan Abdelghani Hassan , "5- A comparative study for the effect of glucose, fructose, sucrol and aspartame", لايوجد, 1900 More
  • Atef Saad Abdelreheem, "Pharmacoloical Studies on the effect of some drus on cardiac Arrhythmias", لايوجد, 1900 More
  • Mohammed Nagieb Mohamed Zakarya Hassan , "The involvement of central cholinergic mechanisms in mediating lithium"s actions. Assuit Med", لايوجد, 1900 More
  • Hany Mohamed Abdelmalek Mahmoud ElBassossy, "Chrysin and Luteolin Attenuate Diabetes-Induced Impairment in Endothelial-Dependent Relaxation: Effect on Lipid Profile, AGEs and NO Generation", Phytotherapy Research, 2013 More
  • Ahmed Fahmy Ahmad, "Chrysin and Luteolin Attenuate Diabetes-Induced Impairment in Endothelial-Dependent Relaxation: Effect on Lipid Profile, AGEs and NO Generation", Phytotherapy Research, 2013 More
Tweet