Apigenin inhibits COX-2, PGE2, and EP1 and also initiates terminal differentiation in the epidermis of tumor bearing mice.

Faculty Pharmacy Year: 2016
Type of Publication: ZU Hosted Pages:
Authors:
Eman Salah Abdelaziz Souliman
Journal: Prostaglandins Leukot Essent Fatty Acids Elsevier Volume:
Keywords : Apigenin inhibits COX-2, PGE2, , , , also initiates    
Abstract:
Non-melanoma skin cancer (NMSC) is the most prevalent cancer in the United States. NMSC overexpresses cyclooxygenase-2 (COX-2). COX-2 synthesizes prostaglandins such as PGE2 which promote proliferation and tumorigenesis by engaging G-protei
    
     
 
       

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