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A freeze-dried (lyophilized) amniotic membrane transplantation with mitomycin C and trabeculectomy for pediatric glaucoma
Faculty
Medicine
Year:
2010
Type of Publication:
Article
Pages:
164-170
Authors:
Mahdy, Reda A, Nada, Waled M, Almasalamy, Salah M, Anany, Hesham A, Almasary, Ayman M
DOI:
10.3109/15569521003775005
Journal:
CUTANEOUS AND OCULAR TOXICOLOGY INFORMA HEALTHCARE
Volume:
29
Research Area:
Ophthalmology; Toxicology
ISSN
ISI:000282187000003
Keywords :
Trabeculectomy, pediatric, glaucoma, mitomycin C, amniotic membrane
Abstract:
Purpose: To evaluate the potential usefulness of a freeze-dried (lyophilized) amniotic membrane transplantation with mitomycin C (MMC) in the maintenance of functioning glaucoma surgery in cases of pediatric glaucoma. Methods:Thirty eyes of pediatric patients with glaucoma were included in this study. Trabeculectomy with amniotic membrane implantation and MMC was done in group 1 (15 eyes), and trabeculectomy with MMC only was done in group 2 (15 eyes). The preserved amniotic membrane was placed over the scleral flap and under the conjunctiva. The mean intraocular pressure (IOP) was measured pre- and postoperatively and bleb appearance was noted, The follow-up time was 18 months after surgery. Results: The mean postoperative IOP was significantly decreased to 15 +/- 1 mm Hg and 17.2 +/- 2.9 mm Hg in the 2 groups, respectively. The bleb was functioning well in the follow-up period in most of the cases, except 5 cases that needed another surgery. Complications such as inflammation, choroidal detachment, or toxic keratopathy were not noted in group 1 but were noted in group 2. Conclusion: Trabeculectomy with amniotic membrane transplantation and MMC can effectively control the elevated IOP in pediatric patients with glaucoma without significant postoperative complications.
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جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
شراقوة
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف