Studies On The Preparation And Quality Control Of 99Mo/99mtc Generator Based On Zirconium Iodomolybdate Gel For Medical Application

The goal of this thesis is divided into two parts:The first part will study:• Synthesis of different types of zirconium iodomolybdate gels .• Characterization of the prepared gels.• Preparation of the active gel, which will be used in 99Mo/ 99mTc chromatographic gel generator.• Elution performance and quality control of prepared 99Mo/ 99mTc chromatographic gel generator.The second part will study:• Radiolabeling of Celecoxib, the selective COX2 inhibitor with 99mTc• Optimization of Celecoxib labeling conditions.• Biological distribution of the labeled complex in normal and inflamed mice.• Quality control of the labeled compound.