Analytical Studies On Some Pharmaceutical Compounds

A Sensitive and selective LC/MS/MS method for determination of ibuprofen in human plasma optimized for avoidance of effects through monitoring phospholipids in the negative ESL mode was developed and validated. The total run time was 7 minutes. A simple liquid-liquid extraction method using 10:90 ethyl acetate: n-hexane v/v at acidic Ph was found to be an effective.