Instrumental analysis Of Cerrtian Fluoroquinlones In Pharmaceutical Formulations\

It discribes the theoretical background and literature review of selected drugs on the reported methods for their determination and also chemical structure, physical properties and mode of action of these cited drugs.An isocratic HpLC method had been developed for rapid simultaneous separation and determination of four fluoroquinolones including levoxacin HCL, lomefloxacin HCL,gatiflooxacin and sparfloxacin in pure form or in presence of some impurities within 5 minutes. separation was carried out on a chromolith performance RP-18e (100 x 4.6 mm )columm. effect of PH and composition of mobile phase in addition to impurities interference