Synthesis and n-alkylation of certain C-substituted Glutarimides

C-Substituted Glutarimides. A brief survey on the versatile biological activi¬ties of C-substituted glutarioiides is presented. In addition the different methods of preparing glutaric acid, its G-substituted derivatives, their anhydrides, and their imides are thoroughly reviewed.The present investigation comprised the synthesis of the following intermediates which are not easily accessible:1) ”Ethyl propane 1,1,3»3-tetracarboxylate2) Glutaric acid3) Glutaric anhydride4) Glutarimide5) Cyanoacetamide6) a ,a’-Dicyano-B-methyIgluturaaide7) 6-Mothylglutaric acid8) B-Methylglutaric anhydride