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New Methodes For The Determenation Of Some Organometallic Pharmaceutical Compounds
Faculty
Pharmacy
Year:
1976
Type of Publication:
Theses
Pages:
295
Authors:
Bahia Abbas Mohamed Mousa
BibID
3206950
Keywords :
Pharmaceutical chemistry
Abstract:
Organometallic Compounds Including Organomercurialas.The theis colsits of four parts :I-inrodustiona-Includes briefy the definition of organometalic compounds and the uses of orgnomercurals and organoarsenicals.b-Incdes historical preface for the production of organomercurias and oranoarsenicals and the pharma – coogical action of organomercurial diuretics.c-Includes the mode of action of these compounds by interfering with the SH- group that are essential for the metatolites of the bactsrial and parasite cell walls with out eliminating that of the host .II-Methods of analysis of crgsnomercurias and organoarsenicalsThis part is classified into:1-Literrrrature review.II-commounts on the published nethods and their criticism.I-Literaturo review:Includs the iterature study of the methds for the analysis of organonmercyry and orgaoarsenic comounds and are classied into gravimetric , volumetric, instru- menta and chromatographic methods.II-comments on the published methous and their criticism:This part iustrates the disadvantages , tediousness, possibility of errers and sensitivity of the methods used for their evaluation .III-Research objective and programmeThis part shows the requirementas for analytica methods that are precise , sensitive and applicable to the determination of organomerculricals .Different methods are tried and roomonded to fufil these needs . At the end of this part , abrief account of the present methods for the evaluation of the mercury and arsenic conten tes as well as other function groups is given .IV- ExperimentalIncludes to part :1-Determination of organomercurials.2-Detemination of organoarsnical.
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