| Abstract: |
Random blood sugar (Hölzle, 2002). Hyperhidrosis is a condition characterized by excessive sweating occurring in up to 1% of the population, with an apparent increased prevalence in countries of the Far East (Schwartz et al., 2009). There are two types of hyperhidrosis according to the etiology Primary hyperhidrosis most commonly occurs spontaneously, or in response to temperature and emotional changes, or as a result of increased sympathetic activity (Gossot et al., 2001 Secondary causes include central nervous system conditions such as disorders of the hypothalamus or pituitary glands, or chronic diseases such as tuberculosis, lymphoma, diabetes, thyrotoxicosis, or pheochro-mocytomas. The areas of the body commonly affected in hyperhidrosis in order of frequency include the palms, feet, axillae, head, or face (Doolabh et al., 2004 The surface of the body is covered with sweat glands of two types: Eccrine and apocrine sweat glands, Eccrine sweat glands secrete a clear odorless fluid that serves to aid thermoregulation by evaporation. Eccrine glands are widespread but present in higher density on the soles of the feet, forehead, and palms. Apocrine sweat glands are restricted to the axillae and groin. Apocrine glands produce a thick fluid that undergoes bacterial decomposition to produce a strong odor. The thermoregulatory center in the hypothalamus controls body temperature by regulating blood flow to the skin and eccrine sweat production (Siperstein and Schwartz, 2010The diagnosis of primary hyperhidrosis can be made on the basis of history and physical examination alone. It occurs in young, healthy patients with a family history, and onset during childhood or adolescence. There is bilateral symmetric involvement of palms, soles, and/or axillae. (Hund et al., 2002).Investigations may be necessary to exclude underlying causes for hyperhidrosis. The most important clues to the presence of secondary hyperhidrosis come from the clinical history and examination. Basic investigations should include full blood count with ESR, urea and electrolytes, liver function tests, thyroid function tests.
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