Hormonal Disturbances And Sexual Performance Affection In Chronic Liver Diseases

Erectile dysfunction is a problem in patients with chronic liver diseases leading to worsening the quality of life in those patients. The controversy about sex hormones disturbance in chronic liver diseases and the effect of sildenafil on the diseased liver for many years has been proposed for research. The introduction of phosphodiesterase type 5 inhibitors (PDE5Is) in 1998 has revolutionized the management of erectile dysfunction. Hormonal disturbances especially in sex hormones and ED occur through different mechanisms and can be diagnosed by several methods. Hormonal disturbances especially in sex hormones and ED can be treated in a multi step manner.