Selective and Orally Bioavailable CHK1 Inhibitors of Some Synthesized Substituted Thieno[2,3-b]pyridine Candidates

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Journal: International Journal of Pharmacology International Journal of Pharmacology Volume:
Keywords : Selective , Orally Bioavailable CHK1 Inhibitors , Some    
Abstract:
A series of the newly substituted thienopyrimidine derivatives 2-13 were synthesized by using 3-amino-6-(4-chlorophenyl)-4-(4-isopropylphenyl) thieno[2,3-b]pyridine-2-carbohydrazide 1 as starting material. Reaction of compound 1 with p-n
   
     
 
       

Author Related Publications

  • Said Ali Said Jaballah, "synthesis and antimicrobial evaluation of some new pyrimidines and condensed pyrimidines", elsevier, 2017 More
  • Said Ali Said Jaballah, "O-Glycosylation/Alkylation and Antimicrobial Activity of 4,6-Diaryl-2- Oxonicotinonitrile Derivatives", J. Heterocyclic Chem, 2016 More
  • Said Ali Said Jaballah, "Synthesis and antimicrobial evaluation of some new pyrimidines and condensed pyrimidines", Arabian Journal of Chemistry, 2016 More
  • Said Ali Said Jaballah, "Synthesis of some fused heterocyclic systems and their nucleoside candidates", Res Chem Intermed, 2013 More
  • Said Ali Said Jaballah, "Synthesis and antimicrobial activities of some newly 2,4,6-tri-substituted pyridine derivatives", Res Chem Intermed, 2013 More

Department Related Publications

  • Mohamed Gamal Helmy Mohamed Abdelwahed, "Electronic Properties of Organic Complexes. 2. Reactive Azodyes", Spain, 1993 More
  • Mohamed Gamal Helmy Mohamed Abdelwahed, "Electrical Behaviour of some Azodye Mixed Ligand with Gd3+ and Er3+. b", Peru, 1994 More
  • Atef Mohamed AbdelHamid Ali Hassn, "heterocyclization of thiouracil derivative: synthesis of thiazolopyrimidines, tetrazolopyrimidines and triazolopyrimidines of potential biological activity", elsevier, 2015 More
  • Ahmed Abdelmoniem Ahmed Amer, "Synthesis and characterization of some calcium aluminate phases from nano-size starting materials", 0366-3175/© 2020 SECV. Published by Elsevier Espana, ˜ S.L.U, 2020 More
  • Hamdy Aldedamony , "Synthesis and characterization of some calcium aluminate phases from nano-size starting materials", 0366-3175/© 2020 SECV. Published by Elsevier Espana, ˜ S.L.U, 2020 More
Tweet