Heterocyclization of thiouracil derivative: synthesis of thia-zolopyrimidines, tetrazolopyrimidines and triazolopyrimidines of potential biological activity

Faculty Science Year: 2015
Type of Publication: ZU Hosted Pages:
Authors:
Said Ali Said Jaballah
Journal: Journal of the Iranian Chemical Journal of the Iranian Chemical Volume:
Keywords : Heterocyclization , thiouracil derivative: synthesis , , thia-zolopyrimidines, tetrazolopyrimidines    
Abstract:
The reaction of thioxopyrimidine derivative 1a with chloroacetic acid and p-chlorobenzaldehyde gave compound 2. Alkylation of 1b using chloroacetonitrile gave N-alkylated derivative 6 which was reacted with hydrazine hydrate to give 7. Co
    
     
 
       

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