Airway Pressure Release Ventilation as a Mode in Management of Acutely Exacerbated chronic obstructive pulmonary disease Patients

This study was carried out to study different mechanical ventilator modes (SIMV, SIMV + PS versus APRV) outcome in AECOPD with respiratory failure, trying to identify possible role of APRV in these patients.For this purpose, 45 patients (29 males and 16 females with a mean age of 61.8±7.6 years) with acute exacerbation of COPD admitted at the Respiratory ICU of Chest Department, Zagazig University Hospitals were included. They were classified according to the mode they received into 3 groups.Group I: They were 15 patients (33,3%) 10 patients (66.67%) of them were males and 5 patients (33.33%) were female ( 12 patients were ventilated from the start by SIMV+PS,while 3 patients changed from APRV mode during 1h because thay can,t tolrated the mode one of them devolped tachycardia(HR>110) and other two patients devolped tachypnea (RR>45) This patients were put on SIMV mode plus PSV (15-22cm H2O) according to the protocol used in our respiratory ICU at Zagazig University Hospitals .Group II: They were 15 patients (33,3%) 10 patients (66,7%) of them were males and 5 patients (33,3%) were femaleThis patients were put on SIMV mode according to the protocol used in RICU at Zagazig University HospitalsGroup III: They were 18 patients(3 patients(2 males ,and 1females) failed to complete on this mode and changed to SIMV+PS during 1h) while the other 15 patients was complete on APRV mode 9 patients.