Spectroscopic and physical measurements on charge transfer complex of norfloxacin drug with iodine acceptor

The charge-transfer complex of the norfloxacin (nor) donor with iodine (I-2) acceptor has been studied spectrophotometrically in chloroform at room temperature using, absorption spectrophotometer. The results pointed to the formation of CT complex. The stoichiometry of the complex was determined. The ratio method between donor and acceptor was found to be 1:1 by molar ratio method. The formation constant (K-CT), molar extinction coefficient (epsilon(CT)), standard free energy (Delta G degrees), oscillator strength (f), transition dipole moment (mu), resonance energy (R-N) and ionization potential (I-D) were estimated. IR. HNMR, mass spectra, UV-Vis techniques, elemental analyses (CHN) and TG-DTG/DTA investigations were used to characterize the structure of charge-transfer complex. It was found that the CT interaction is associated with a proton migration from the donor to iodine followed by intermolecular hydrogen bond. In addition X-ray investigation was carried out to scrutinize the crystal structure of the complex.