Study of serum c-reactive protein in patients with thyroid diseases

C-Reactive Protein (CRP) is one of the acute phase proteins that increase in systemic inflammation It is produced by the liver and fat cells (Gurven et al., 2008).Previous studies have reported marked variations in serum CRP levels with different thyroid disease (Pearce et al., 2003).The study of Hueston et al., (2005) showed no difference in CRP levels between patients with subclinical hypothyroidism and euthyroid individuals.Study of Tuzcu et al., (2007) has shown clear association between hypothyroidism and a raised CRP. Elevated serum CRP levels in sub acute thyroiditis patients reported by Pearce et al., (2003).A more recent study by Fatourechi , (2009) reported significant association between a raised CRP and subclinical hypothyroidism in patients with metabolic syndrome.The situation in cases of hyperthyroidism is not different, and this reported at the study by Czarny , ( 2004) he found high levels of CRP in patients with Graves ophthalmopathy, while Chu et al., (2008) found no difference in serum CRP between hyperthyroidism and control group and in another hand he found also there is no difference among hyperthyroidism group before and after treatment.However ,CRP estimation have not been routinely used to monitor thyroid disease , although many thyroid conditions involve inflammation (Rao et al.,2010).