left ventricular diastolic function in patients with heart failure and preserved ejection fraction

Faculty Medicine Year: 2011
Type of Publication: Theses Pages: 145
Authors:
BibID 11233036
Keywords : Cardiology    
Abstract:
”Summary: Left ventricular heart failure in the setting of a preserved left ventricular ejection fraction constitutes up to 50% of heart failure, increases with age, is correlated with the presence of systemic hypertention and left ventricular hypertrophy, and has significant morbidity and mortality, approaching that of systolic heart failure. Predisposing conditions for DHF are older age, female gender, diabetes and obesity, arterial hypertension, and left ventricular (LV) hypertrophy. Diagnosis of heart failure with normal ejection fraction requires the following conditions to be satisfied: (i) signs or symptoms of heart failure; ii) normal or mildly abnormal systolic LV function; (iii) evidence of diastolic LV dysfunction. Diagnostic evidence of diastolic LV dysfunction can be obtained invasively (LV end-diastolic pressure 16 mmHg or mean pulmonary capillary wedge pressure 12 mmHg) or non-invasively by tissue Doppler, blood flow Doppler of mitral valve or pulmonary veins, and echo measures of LV mass index or left atrial volume index. The study has included 50 patients with symptoms suggestive of congestive heart failure and coronary artery disease (typical exertional angma and positive exercise stress test, previous coronary brangiography, or history of myocardial infarction) scheduled for left sided heart catheterization. 113 
   
     
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