Vitamin D as a marker of arterial calcification and cardiovascular risk in children on regular haemodialysis

in our study, we studied the relationship between vascular calcifications, cardiovascular risk factors especially (left ventricular mass index) and 25-hydroxyvitamin d3 [25(oh)d3] and 1,25-dihydroxy-vitamin d3 [1,25(oh)2 d3] serum levels in children on regular hemodialysis which is represented by several parameters.in our study, there was a deficiency of [25(oh)d3] and [1,25(oh)2d3] serum level.in our study, there was increased left ventricular mass index (lvmi) which indicates left ventricular hypertrophy.a significant positive correlation (+ve correlation) between left ventricular mass index (lvmi) and duration of dialysis was detected.there was a highly significant positive correlation between left ventricular mass index (lvmi), blood urea nitrogen and parathormone pth and significant positive correlation with creatinine.there was a significant negative correlation between left ventricular mass index (lvmi), hemoglobin and 25(oh) d3 and a highly significant negative with 1,25(oh)2 d3.in our study, no significant correlation between left ventricular mass index (lvmi), albumin, calcium, phosphorus, ferritin and iron.we found a significant negative correlation between [25(oh)d3] & [1,25(oh)2d3] serum level and parathormone.