Role of endometrial biopsy in infertility

Infertility or the inability to conceive is a problem of global proportions, affecting between 8 and 12 percent of couples worldwideIn a developing country like Egypt, where complex expensive immunological and hormonal assay procedures are not easily available or affordable, endometrial biopsy is a valuable investigation for primary infertility,. Proper correlation, histological finding with dating of endometrium, helps to diagnose functional abnormalities of the endometrium as well as intrinsic abnormalities such as tuberculosis, most of whom are otherwise asymptomatic patients of infertility. One hundred endometrial samples from infertility cases were studied and full secretory endometrium was detected in 47 cases (47%), Abnormal endometrium was detected in 53 cases (53%). Out of these (2%) were endometritis represented as 1% chronic non specific endometritis and 1 % as tuberculous endometritis. The remaining 51% of all cases were due to hormonal disturbances represented as (20%) proliferative endometrium suggestive of anovulatory cycle, (13%) insufficient secretory endometrium, (7%) were hyperplasia (4%) atrophic endometrium, 1% endometrial polyps and 1% Adenomyosis.