Disease Presentation And Management Practices Of Childhood Immune Thrombocytopenic Purpura

ITP is the most common bleeding disorder of childhood acvompanied by many controversies in the diagnosis and management. We aimed to report our experience with such heterogeneous diseaseProcedure: Retrospective study of medical records of 202 children with itp in pediatric department¸ Zagazig university hospital between January 2005 and December 2010 was doneResults: The mean age of presentation was 4.5 ± 2.9 years. Male to female ratio was 1.1: 1. 57.9% of patients had preceding infection. Only 2 cases developed Intracranial hemorrhage. Higher incidence of cases was reported in spring and winter. 20% of cases were managed conservatively. Steroids were the main first line treatment and it had nearly equal response to IVIG. The rate of chronic ITP was 17.8% and chronic ITP was more common in older children specially in females absence of preceding URTI and low response to first line therapy were predictors of chronic ITP.