| Abstract: |
ovarian cancer is deadly and frequently affects older patients. In the next 20 years, the number of patients over 65 will double, and cancer, including ovarian cancer, will increase in incidence. Older patients with ovarian cancer did not have reduced survival rates compared to younger patients, but they were more likely to undergo suboptimal surgery and to have more advanced disease. Preoperative serum CA 125 measurements did not identify patients in the older age group for whom surgery would be optimal (Renaud MC.,et al., 2010).Ultrasound characteristics can be used to diagnose the classic-appearing nonneoplastic entities, benign neoplasms and malignancies. In cases in which the appearance of an ovarian mass is not classic, assignment of relative risk of malignancy using a multiparametric model is appropriate and beneficial for patient management (Twickler.,et al., 2010).Ovarian cancer represent one of lethal malignancy if not discovered early. Most cases present in late stages, so early detection of cancer ovary is one of important item many researches try by different modalities for establishing the one or more methods for detection.This study designed for evaluation of the CA125, examinations, ultrasound (2D& 4D), Doppler study, reevaluation of validity of risk of malignant index. By this study we found the significance of CA125, ultrasound data (solid areas, papillae, the widest diameter) , and risk of malignant index. By addition of Doppler data (PI& RI) the significance become more , and hence , by use statistical analysis of multiple variables by which the significance become more and more with sensitivity of 90.9%, specificity 88.4%, positive predictive value 93.3%, and negative predictive value 84.4%.There is no significance from cigarette smoking, clomiphine citrae, FSH, and LH for cancer ovary development.
|
|
|