Sustained release rectal suppositories as drug delivery system for atenolol

Faculty Pharmacy Year: 2012
Type of Publication: ZU Hosted Pages:
Authors:
Fakhreldeen Soliman Ghazy Shehata
Journal: J.Amer>sci J.Amer>sci Volume:
Keywords : Sustained release rectal suppositories , drug delivery    
Abstract:
Atenolol suppositories were prepared using either hydrophilic bases of PEG or hydrophobic emulsifying bases such as witepsol H15 .Interestingly,atenolol showed high release rate from both bases due to its low partition coefficient and high
   
     
 
       

Author Related Publications

  • Fakhreldeen Soliman Ghazy Shehata, "Treatment of pulmonary arterial hypertension by vardenafil-solid dispersion lozenges as a potential alternative drug delivery system", Elsevier, 2020 More
  • Fakhreldeen Soliman Ghazy Shehata, "Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues", Elsevier, 2019 More
  • Fakhreldeen Soliman Ghazy Shehata, "Pediatric suppositories of sulpiride solid dispersion for treatment of tourette syndrome :invitro and invivo investigations", ِِِِِAAPS pharm tech, 2014 More
  • Fakhreldeen Soliman Ghazy Shehata, "Solid dispersion approach for optimized bioavailability of sulpiride", Lat.Am.j.Pharm, 2013 More
  • Fakhreldeen Soliman Ghazy Shehata, "Formulation and pharmaceutical evaluation of metoclopramide HCL floating capsules", IJAPR, 2013 More

Department Related Publications

  • Ahmed Samer Zedan, "Physicochemical characterization and dissolution properties of rofecoxib complexes with cyclodextrins", لايوجد, 1900 More
  • Ahmed Samer Zedan, "Preparation and characterization of rofecoxib solid dispersions with polyethylene glycols and urea", لايوجد, 1900 More
  • Mahmoud Mokhtar AhmedIbrahiem, "Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes", لايوجد, 1900 More
  • Amr Selim Ahmed Ali Abu Lila, "Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration", Elsevier, 2013 More
  • Amr Selim Ahmed Ali Abu Lila, "Tumor-type-dependent vascular permeability constitutes a potential impediment to the therapeutic efficacy of liposomal oxaliplatin", Elsevier, 2012 More
Tweet