Histological and Histochemical Study Of The Effect Of The Fungicide”Carbendazim” On The Testis Of Albino Rats

Sperm count in healthy men around the world has fallen about 50 percent in the last 50 years. The problem of infertility has increased from 8% to 15% over the last two decades in industrialized countries It was revealed that exposure to toxic chemicals may be an important cause of sperm count decline which can affect male fertility in more than one way Despite the beneficial effects associated with the use of pesticides in plant protection and public health programs, many of these chemicals represent a potential hazard to human and to nature. This attracts the attention of many studies to their toxic potential (Carpy et a1., 2000).Some epidemiological studies on agriculture workers, chemical industry workers and other exposed individuals have shown a positive association between pesticides exposure and reduced fertility among men as well as male mediated adverse reproductive outcomes, like spontaneous abortion and congenital anomalies About 200 million pounds of sperm damaging pesticides are used in agriculture every year. Over 50 pesticides are known to disrupt sperm production or male hormones. Carbendazim (methyl 2-benzimidazole carbamate) is one of these commonly used pesticides in both agriculture and household situation