Left ventricular function in patients with chronic Kidney Disease

Cardiovascular complications are the most frequent cause of death in children with chronic renal failure.This study was conducted on 40 children with chronic renal failure (17 male and 23 female) their age ranged from 8 years to 17 years attending the Nephrology Unit of the Pediatric Hospital Zagazig University. All children were subjected to thorough history taking, complete detailed clinical examination and laboratory investigations including CBC, Kidney function tests, serum electrolytes, iron, ferritin and PTH level were assessed.All cases and control were assessed by conventional echocardiography, tissue Doppler velocity and strain imaging before and after dialysis to determine the structural and functional abnormalities of right and left ventricle and to detect load effect on cardiac functions.Systolic functions were assessed by conventional echocardiography including (FS% &EF) both of them were normal in our cases and showed no significant change after dialysis.Diastolic functions were assessed by conventional echocardiography using mitral and tricuspid inflow velocities peak early velocity (E), peak late velocity (A), E/A ratio.