Relationship Between Right Ventricular Systolic Activation Delay and Pulmonary Arterial Hypertension: A Tissue Doppler study

Introduction: pulmonary arterial hypertension, mean pulmonary artery pressure more than 25 mmHg at rest or 30 mmHg during exercise (Cool et al., 2005), Tissue Doppler Imaging (TDI) has an objective means to quantify global and regional Left Ventricular (LV) and RV function with improved accuracy and greater reproducibility than conventional echocardiography (De Backer et al., 2005).Aim of Work: to evaluate TDI to investigate abnormalities in RV myocardial systolic activation and it’s relation to RV dysfunction in patient with pulmonary artery hypertension.Patients and Methods: The study included 29 patients with pulmonary artery pressure more than 25 mmHg at rest or systolic pulmonary artery pressure more than 35 mmHg and 10 health subjects. They were classified into three groups:Group І (secondary pulmonary hypertension): It included 20 patients.Group ІІ (primary pulmonary hypertension): It included 9 patients.Group ІІІ (control): It included 10 healthy control subjects.All the examined subjects were subjected