Highlight on interventional management in neurological disorders

Intervention is literally defined as the act or the method of interfering with the course or outcome of a condition or a process to prevent harm and or improve functioning using minimally invasive procedures which developed to offer good clinical results combined with a well-tolerated, low-cost procedure (Andreula 2003).Neurovascular interventional procedures can be applied in clinical practice to a broad range of cerebrovascular diseases through embolization which leads to occlusion of feeding blood vessels in cerebrovascular malformations, and revascularization which leads to reopening of occluded blood vessels especially in ischaemic strokes (Kirmani et al. 2005).The growth of stem cell biology over the past few decades, has created considerable excitement and hope that it can be used for transplantation, gene therapy, and even tissue regeneration or organogenesis (Sadiq and Gerber 2004).Stem cell therapy as well is considered as a cellular neurorestorative approach that used to facilitate recovery of neurological function through the induction of neurogenesis, angiogenesis, and synaptic plasticity. It can be of great value in different categories of central nervous system (CNS) diseases like neuro-degenerative, demyelinating diseases, cerebral ischaemia and spinal cord injury (Zietlow et al. 2008; Dharmasaroja 2009).Another line of interventional techniques is the stereotactic radiosurgery (SRS) which defined as a closed skull destruction of intracranial target lesion precisely defined according to a fixed coordinate system with a single dose of ionizing irradiation without surgical intervention (Abdulla 2002)..